| January 18 |
Go over syllabus, Introduction to
Computational Molecular Biology |
| January 20 |
DNA, RNA, Protein, NCBI |
| January 23 |
Quiz 01, Finding information at NCBI, Introduction to pairwise sequence
alignment |
| January 25 |
Dot matrix method, Pairwise sequence
alignment, Substitution matrices |
| January 27 |
Pairwise alignment,
Homework 01 due |
| January 30 |
Quiz 02, Pairwise alignment |
| February 1 |
Amino acid substitution matrices,
|
| February 3 |
Multiple sequence alignment
|
| February 6 |
Homework 2 due, Quiz 3 Database searching
|
| February 8 |
Database searching
|
| February 10 |
Homework 3 due, Phylogenetic analysis
|
| February 13 |
Quiz 4 Phylogenetic analysis
|
| February 15 |
Phylogenetic analysis
|
| February 17 |
Exam 1 |
| February 20 |
Markov models |
| February 22 |
Gene finding
|
| February 24 |
Homework 4 due, Gene finding
|
| February 27 |
Quiz 5, Protein motif prediction |
| March 1 |
Protein motif prediction |
| March 3 |
Exam 2 |
| March 6 |
Protein structure prediction |
| March 8 |
Distribution of class projects |
| March 10 |
Homework 5 due, Protein structure prediction |
| March 13, 15, 17 |
Spring break
|
| March 20
| Sequence assembly
|
| March 22 |
Sequence assembly |
| March 24
| Homework 6 due, Sequence assembly |
| March 27 |
Gene expression data |
| March 29 |
Gene expression data
|
| March 31 |
Gene expression data
|
| April 3 |
Progress reports on projects |
| April 5 |
Exam 3
|
| April 7 |
Computational Proteomics |
| April 10 |
Computational Proteomics
|
| April 12 |
Computational Proteomics
|
| April 14 |
Holiday |
| April 17 |
Progress reports on projects
| April 19 |
RNA secondary structure prediction |
| April 21 |
RNA secondary structure prediction
|
| April 24 |
Papers on projects due at the beginning of class,
project presentations
|
| April 26 |
Project presentations |
| April 28 |
Project presentations
| May 1 |
Selected topics
|
| May 3 |
Selected topics
|
| May 5 |
Final Exam, 8 am - 11 am |
| |
